After the Holidays” is now, and we are back to the blessed routine.
Welcome to DigitalRosh CONNECT — still in beta form — DigitalRosh newsletter where we support lifelong learning by opening the mind to new directions, trends, and other DigitalRosh new.
This week in our newsletter:
1. Info Source: “WhatIsBiotechnology”
2. DigitalRosh LIVE: Q4 series WEAVING DIGITAL
3. Study: The CMO as a Key Driver of Organizational Growth (McKinsey)
4. Guide: Definitive guide to ransomware 2022 (IBM Security)
5. Metaverse: How to Build a Metaverse (Wall Street Journal)
6. Person of the week: Prof. Jennifer Doudna
New section “Person of the week” is dedicated to our front presenter where we will share info about the CONNECT Leader of the week
Wishing you Shana Tova and enlightening learning,
Prof. Yesha Sivan, Founder, and CEO
& DigitalRosh team
נ.ב. לדוברי העברית. כן המשיח בדרך והוא מדבר אנגלית.
ה”חדשות” שלנו עוברות לאנגלית — עם מיתוג חדש שנקרא CONNECT. בשבועות הקרובים בבטא…
(1) DigitalRosh > Corpus > Guide and Tools > Info Sources
Info Sources: What Is Biotechnology?
“WhatIsBiotechnology” היא פלטפורמה חינוכית וציבורית מובילה, המאגדת סיפורים על המדע, האנשים והמקומות שאפשרו לביוטכנולוגיה לשנות את הרפואה ואת העולם בו אנו חיים היום. האתר מציע גם לחקור ציר זמן רחב של אירועים משמעותיים ולסנן לפי קטגוריות ספציפיות: שם המדענ/ית, מקום האירוע וסוג המדע.
WhatIsBiotechnology is a leading educational and public engagement platform that brings together the stories about the sciences, people and places that have enabled biotechnology to transform medicine and the world we live in today. This site also offers to explore a wide timeline of scientific events and to filter by specific categories: name of scientist, place of the event, and by science.
Public engagement is one of the missions of “WhatIsBiotechnology”. They aim to produce compelling, interactive resources including videos, posters, and exhibitions that empower people by helping them access, use, respond to and create health research and innovation.
Much of this will be developed in partnership with researchers and health professionals.
Where it generates engagement these projects will be taken into the community to engage with people on the ground in schools, healthcare facilities, libraries, and public spaces. They will also be placed in interactive exhibitions online so that people around the world can access, use and respond to them.
An important part of the mission is to help researchers and health professionals create people-centered health research so as to that help improve their understanding of people’s experiences when they access healthcare.
They aim to help researchers and policy-makers around the world to promote debate, and frame proposals for action to improve engagement and trust in science and healthcare.
Some of the subjects you can find on this site are:
The history of the organ-on-a-chip
The history of messenger RNA (mRNA)
Raising awareness of antimicrobial resistance
The COVID-19 pandemic
Women in biotechnology
Conquering Hepatitis B: A revolution for public health and vaccine safety
This day in biotechnology: events took place on every certain day in years past
People
Timeline of key events in Biotechnology
(2) DigitalRosh > Community > DigitalRosh Live
DigitalRosh LIVE: Q4 series WEAVING DIGITAL
דיגיטלראש לייב, תכנית וובינרים מיוחדת, לחברי וחברות דיגיטלראש. 5 מפגשים באנגלית המקיפים נושאים מגוונים עם אנשי מקצוע ברמה עולמית: ניהול בעולם משתנה עם מקינזי, דיגיטציה ברשויות המס והביטוח, למידה דיגיטלית בהרווארד והבנה כיצד זה אפשרי בעזרת ה-AI של אמזון. מנחה ועורך ראשי: יעקב אילון.
ימי שלישי, 18:00 החל מ-15 בנובמבר, 2022. לאחר ההרצאה תתקיים שיחה פתוחה. חינם למנויי דיגיטלראש-פרו בהרשמה מראש. https://digitalrosh.com/drl-weaver-series-q4-2022
אם אין לך מנוי דיגיטלראש-פרו, אנו מזמינים אותך להרשם כעת למנוי Pro Beta במחיר של 28 ש”ח לחודש בלבד.
Weaving Digital, Q4 2020 DigitalRosh LIVE series, Five sessions with world-class leaders on
Digital learning from Harvard, Artificial Intelligence from Amazon, change management with McKinsey, and innovation at Harel, Israel’s largest insurance player.
The lecturers:
David Perkins – Founding member of Harvard Project Zero – on learning
Merav Ash (Hason) – EMEA Head of ML Business Development, Startups & VC, Amazon Web Services – about AI
Gila Tolub – Partner, Leader of Health Tech Hub, McKinsey – Change management
Arie Rimini – General Manager of Israel Tax Authority IT (Shaam) – on digital taxing and taxing digital
Elior Zoaretz – Deputy CEO Head of Business Dev & Innovation, HAREL – Weaving digital insurance and infusion of innovation
Join us for unique, fascinating, and meaningful meetings on Tuesdays, 18:00 to 19:00, for a lecture with senior executives, each from a leading company in their field at the digital front. The lectures will be followed by an open discussion from 19:00-19:45, in which the audience can participate
Participation is limited to DigitalRosh Pro members – free of charge, subject to registration
You can sign up for the full series with the button below, or for each of the meetings separately
If you are not a DigitalRosh Pro member yet, you are invited to join us now with a special discount at a monthly fee of NIS28 only (equivalent to 8$/month) via DigitalRosh Pro Beta
Upon Sign up to DigitalRosh Pro you will be registered automatically to the series’ meetings:
(3) DigitalRosh > Corpus > Function > Marketing Study: The CMO as a Key Driver of Organizational Growth (McKinsey)
על פי מקינזי, 83% מהמנכ”ליות והמנכ”לים מאמינים ששיווק יכול להיות מניע מרכזי לצמיחה. הניתוח של מקינזי מגלה שיכולת השיווק להניע צמיחה תלויה במידה רבה בחוזקן של השותפויות שה-CMO מצליח לייצר ברחבי הארגון. הם מאבחנים 3 טיפוסים של מנהלי/ות שיווק – מאחד/ת, מתבודד/ת, חבר/ה. רק מנהלי/ות שיווק מהסוג המאחד מצליחים לייצר שותפויות משמעותיות ופרודקטיביות בארגון, אשר מהוות גורם מניע לצמיחה ארגונית.
במחקר של מקינזי תאור של שלושת הטיפוסים, מסלול הפעולה שלהם ופוטנציאל ההשפעה בארגון.
In a new McKinsey study, 83 percent of global CEOs say that marketing can be a major driver of growth. For a function that has all too often been thought of as the “brand” or “advertising” arm of the business, this is a notable development. But the news isn’t all rosy. Some 23 percent of CEOs do not feel that marketing is delivering on that agenda, and the view elsewhere in the C-suite is even more mixed. One group of CMOs, however, has figured out how to deliver on the growth promise.
According to a model called “marketing with a capital M” diverse areas of the organization—from sales and product innovation to finance, technology, and HR—participate in marketing’s success and see themselves as partners in its mission.
As head of marketing, the CMO has a crucial role to play in driving organizations toward this vision, and the stakes are high. McKinsey’s analysis reveals that a marketing organization’s ability to drive growth depends heavily on the strength of the partnerships the CMO can forge across the organization. They call these CMOs Unifiers.
McKinsey divides all CMOs into three types, each with distinctive habits and traits: the Unifier, the Friend, and the Loner. However, only one — the Unifier — is the key to future victory.
In the article, McKinsey presents the three archetypes of CMOs, their course of action, and their potential influence on the organization.
(4) DigitalRosh > Corpus > Technologies > Cyber
Guide: Definitive Guide to Ransomware 2022 (IBM Security)
מסמך של IBM SECURITY שנועד להעלאת המודעות בארגונים להתקפות כופרה ומדריך כיצד להתמודד איתן.
ansomware is an online attack perpetrated by cybercriminals or nation-state-sponsored groups who demand a monetary ransom to release their hold on encrypted or stolen data
In the past decade, ransomware attacks have evolved from a consumer-level nuisance of fake antivirus products to sophisticated malware with advanced encryption capabilities that target primarily public and private sector organizations. While threat intelligence can help uncover what organizations may be considered primary targets at any given time, no single industry, geography, or size of business is immune. As the footprint of ransomware keeps growing, so too does the amount of ransom demanded to release data. Ransom amounts that used to total only double digits have grown to seven-figure and eight-figure numbers
This document, created by IBM security, is intended to be used as a guide to help organizations fortify knowledge and defenses against ransomware threats, or more rapidly remediate an evolving situation if an attack occurs. Distinct sections address phases both before and during an attack, with the most critical and time-sensitive being in the initial response section
Ransomware has evolved along a third axis as well: the digital extortion business model. In this model, criminals escalate the attack in order to force payment from victims. If victims fail to pay within the allotted time or opt to recover encrypted data through backups, criminals threaten to release confidential data publicly. Some attackers even auction confidential data to the highest bidder on the dark web. And in another twist, adversarial nation states sometimes blend ransomware with destructive attacks ultimately aimed at destroying and disrupting operations
Ransomware is one of the cybercrime’s strongest business models today, pushing aside long-held staples like banking trojans, phishing, distributed denial-of-service (DDoS), and crypto-jacking. Some criminals use those models as an initial stepping-stone to an eventual targeted attack
The ransomware crime model has harmed organizations across the globe, costing well into billions of U.S. dollars every year. In an even darker turn, ransomware has begun reaping a toll on human life. These attacks that can impact hospitals and affect medical devices have come to be known as “killware” in the industry because of their potential to indirectly cause mortality
The document, created by IBM Security, provides guidance to organizations before and during a ransomware attack. It’s designed to help organizations understand the critical steps needed to protect their business before an attack can penetrate their defenses and achieve optimal recovery if adversaries breach the perimeter.
(5) DigitalRosh > Corpus > Technologies > Metaverse
Metaverse: How to Build a Metaverse, Part 2 (Wall Street Journal)
כאשר Second Life הושק רשמית בשנת 2003, היה לו עיקרון מנחה אחד לכל המשתמשים החדשים: תהיו נחמדים. אבל משתמשים מסויימים הופיעו עם רעיונות משלהם לגבי איך להתנהג בעולם וירטואלי.
בחלק 2 של הפודקאסט איך לבנות מטאוורס, Linden Lab- החברה שיצרה את Second Life – מספרת כיצד נאבקה לשלוט בעולמה החדש.
When Second Life officially launched in 2003, it had one guiding principle for all new users: Be Nice. But those users showed up with their own ideas about how to behave in a virtual world. In part 2 of How to Build a Metaverse, Linden Lab — the company that created Second Life — wrestles with how to govern its new world.
Just as a reminder for part 1:
Nearly two decades before companies like Meta began pouring billions of dollars into the metaverse, a little company called Linden Lab already had one.
In Part 1 of their podcast series, Kate Linebaugh and Ryan Knutson, from Journal podcast, met wth the programmers who built Second Life – a 3D virtual world where users could be and do whatever they could imagine. They also met with the intrepid users who were the pioneers of this brave new world.
(6) DigitalRosh > Corpus > Technologies > Biotechnology
Person of the week: Prof. Jennifer Doudna
פרופ’ ג’ניפר דאודנה (Jennifer Doudna) היא ביוכימאית אמריקאית, המכהנת כפרופסור באוניברסיטת קליפורניה בברקלי. מחקריה הבולטים עוסקים בתחום הקריספר ו-ncRNA. כלת פרס וולף לרפואה לשנת 2020 על “חשיפת המנגנון הצפוי לחולל מהפכה בעולם הרפואה, של חסינות חיידקית באמצעות עריכה מונחית RNA של הגנום”, בנוסף זכתה בפרס נובל לכימיה לשנת 2020 (יחד עם עמנואל שרפנטייה).
דאודנה התפרסמה לראשונה על ידי חשיפת המבנה והתפקוד הבסיסיים של הריבוזום הראשון, סוג של חומצה ריבונוקלאית קטליטית (RNA) המסייעת לזרז תגובות כימיות. עבודה זו סייעה בהמשך להקמת CRISPR-Cas9 – כלי לעריכת גנים בקנה מידה חסר תקדים ובעלות מינימלית.
Prof. Jennifer Doudna first made her name uncovering the basic structure and function of the first ribozyme, a type of catalytic ribonucleic acid (RNA) that helps catalyse chemical reactions. This work helped lay the foundation for her later helping to pioneer CRISPR-Cas 9, a tool that has provided the means to edit genes on an unprecedented scale and at minimal cost. In addition to her scientific contributions to CRISPR, Doudna is known for spearheading the public debate to consider the ethical implications of using CRISPR-Cas9 to edit human embryos.
She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, “for the development of a method for genome editing.” She is the Li Ka Shing Chancellor’s Chair Professor in the Department of Chemistry and the Department of Molecular and Cell Biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997.
Doudna’s doctorate proved to be just the beginning of a long career trying to work out the chemistry underlying RNA’s many biological functions. Like many around her, she was intrigued by the idea that RNA could provide some clues about the origins of life.
Following her doctorate, Doudna spent some time working with Szostak and then left to take up a postgraduate fellowship in the laboratory of Thomas Cech at the University of Colorado in Boulder. One of the attractions of going to work with Cech was that he had just won the Nobel Prize, in 1989, for discovering the catalytic properties of RNA.(Marino) He also had the equipment to carry out X-ray diffraction which would help her decipher the three-dimensional atomic structure of RNA. With no formal training in x-ray diffraction, Doudna spent many of her early days in Cech’s laboratory acquiring the skill alongside crystallising RNA molecules in preparation for imaging them.
In 1994 Doudna left Cech’s laboratory to take up a position as an assistant professor at Yale University. Six years later she was promoted to become the Henry Ford II Professor of Molecular Biophysics and Biochemistry. In 2002, Doudna moved to the University of California, Berkeley, where she was appointed Professor of Biochemistry and Molecular Biology. Berkeley was particularly appealing to Doudna because it allowed her to be closer to her mother in Hawaii and her extended family. It also gave her access to the facilities of the Lawrence Berkeley National Laboratory. She was particularly keen to use the Laboratory’s synchroton, a huge machine that provides high intensity X-ray beams. This would provide her with the means her to delve deeper into the complex structure of proteins and other molecules (Russell).
More about Prof. Jennifer Doudna
https://doudnalab.org/
https://www.whatisbiotechnology.org/index.php/people/summary/Doudna
